MSc Genomic Medicine

A flexible, multi-disciplinary and multi-professional perspective in genomics applied to clinical practice and medical research.

Award titles

MSc

Duration: 1 year FT / 2 years PT
ECTS: 90 ECTS credits
(including PG Cert and PG Dip)

Postgraduate Certificate

Duration: 4 months FT / 1 year PT
ECTS: 30 ECTS credits
(standalone course)

Postgraduate Diploma

Duration: 8 months FT / 2 year PT
ECTS: 60 ECTS credits
(including PG Cert)

Key information

Start date: September 2019
Campus: Various

Apply nowRegister your interest

Overview

Our degrees in Genomic Medicine cover all aspects of genomic science and medicine, and will equip you with the knowledge and skills to be able to interpret and understand genomic data that increasingly impacts on service delivery to patients and the community.

The programme is aimed at students from a wide range of backgrounds, from basic scientists to all levels of healthcare professionals, and will provide a flexible, multi-disciplinary and multi-professional perspective in genomics, applied to clinical practice and medical research.

It is designed to equip you with the knowledge and skills to be able to interpret and understand genomic data that increasingly impacts on service delivery to patients and the community.

The training provided covers all aspects of genomic science and medicine (not merely DNA sequencing or detection of genetic variation), undertaken in one of the most cutting-edge scientific environments.

The course includes collaborations with:

  • the Institute of Cancer Research (providing the core Cancer Genomics Module)
  • Brunel University London (providing the optional Economic Evaluation in Human Genomics Module)

The Institute of Cancer Research and Brunel University London may also co-supervise research projects.

The programme is one of the preferred providers for Health Education England and upholds the values of the NHS Constitution.

Study programme

This course is made up of three progressional levels (PG Cert, PG Dip and MSc), and you can apply to any level in the first instance. Read more about how this works under 'Choosing your course' in the how to apply section.

One of the core modules available within the Master's degree (MSc) includes opportunities to access the emerging data from the 100,000 Genomes Project through the Genomics England Clinical Interpretation Partnership (GeCIP) training domains.

Meet our students

Hear from Genomic Medicine students and graduates on the National Heart and Lung Institute website.

Structure

Modules shown are for the current academic year, and are subject to change depending on your year of entry.

Please note the curriculum of our postgraduate degrees is currently being reviewed as part of a College-wide process to introduce a standardised modular structure. As a result, the content and assessment structures of this course may change for your year of entry. We therefore recommend that you check this course page before finalising your application and after submitting it as we will aim to update this page as soon as any changes are ratified by the College.

As a preferred training provider for Health Education England, this course plays an important role in ensuring NHS staff have the knowledge, skills and experience required to stay at the forefront of this essential field. We have made minor improvements to the course content that will come into effect in October 2018 to ensure that our education continues to respond to the needs of modern healthcare practice.

NHS and Public Health England employees can now apply for a HEE Genomics Education Programme scholarship to cover the tuition fees for individual modules, or longer programmes such as the PG Cert, PG Dip or the Masters. To find out more about this funding and apply please visit the HEE GEP website.

Please note that due to funding restrictions there are limited HEE GEP-funded places available on the October intake. Success in the HEE GEP scholarship application does not guarantee an HEE-funded place at Imperial College London.

Structure

MSc

Core modules

Fundamentals in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Optional modules

Group 1

You choose one optional module from below.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genomics and the Patient

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Group 2

You choose one optional module from below.

Pharmacogenomics and Stratified Medicine

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. Module Leader: Dr Letizia Foroni.

Economic Evaluation in Human Genomics

Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. Module Leader: Dr Subhash Pokhrel.

Genome-Based Therapeutics

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Research project

You will complete a 14 week-full time or one-year part-time research project as part of the MSc. We offer four types of project:

  • laboratory-based
  • clinical-based
  • computer-based
  • literature-based

Assessment is by written dissertation and an oral presentation.

Research projects may be supervised at Imperial, or co-supervised at Imperial and the Institute of Cancer Research or Brunel University London.

Postgraduate Certificate

Core module

Fundamentals in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Optional modules

You choose three optional modules in total.

Group 1

You choose between one and three optional modules from below.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Group 2

You can choose up to one optional module from below.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genomics and the Patient

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Group 3

You can choose up to one optional module from below.

Pharmacogenomics and Stratified Medicine

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. Module Leader: Dr Letizia Foroni.

Economic Evaluation in Human Genomics

Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. Module Leader: Dr Subhash Pokhrel.

Genome-Based Therapeutics

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Postgraduate Diploma

Core modules

Fundamentals in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated.

Bioinformatics, Quality Control, Analysis and Interpretation of Sequencing Data

Provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Optional modules

Group 1

You choose one optional module from below.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genomics and the Patient

Concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Group 2

You choose one optional module from below.

Pharmacogenomics and Stratified Medicine

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. Module Leader: Dr Letizia Foroni.

Economic Evaluation in Human Genomics

Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine. Module Leader: Dr Subhash Pokhrel.

Genome-Based Therapeutics

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research.

Teaching and assessment

Teaching methods

  • Computer lab teaching
  • Data analysis sessions
  • Debates
  • Discussion sessions
  • Interactive content including video and module quizzes
  • Journal clubs
  • Keynote lectures
  • Laboratory teaching
  • Lectures
  • On-line discussion forums
  • On-line lecture materials
  • Problem-based group work
  • Seminars

Assessment methods

  • Coursework
  • Practical
  • Research project (MSc only)

Course timetable

A blended approach to learning is used, in both core and optional modules, combining face-to-face teaching and online distance learning. This is to provide flexibility for health professionals to combine their study with work.

Most modules will consist of one week of face-to-face teaching and up to three weeks of e-learning and independent study. The modules are offered on a cycle of 12 months, so that all modules become available once in each 12 month cycle.

The course is flexible and modular and is available as a full-time or part-time MSc delivered over one or two years respectively. There are also full-time and part-time Postgraduate Certificate (PG Cert) and Postgraduate Diploma (PG Dip) options.

Entry requirements

We welcome students from all over the world and consider all applicants on an individual basis.

Admissions

Minimum academic requirement

Our minimum requirement is a 2.1 degree in a relevant medical, biomedical or healthcare subject.

In special cases students may be admitted to this course with high-quality work experience in place of the above requirement.

International qualifications

The academic requirement above is for applicants who hold or who are working towards a UK qualification.

We also accept a wide variety of international qualifications. For guidance see our Country Index though please note that the standards listed here are the minimum for entry to the College.

If you have any questions about admissions and the standard required for the qualification you hold or are currently studying then please contact the relevant admissions team.

English language requirement (all applicants)

All candidates must demonstrate a minimum level of English language proficiency for admission to the College.

For admission to this course, you must achieve the higher College requirement in the appropriate English language qualification. For details of the minimum grades required to achieve this requirement, please see the English language requirements for postgraduate applicants.

How to apply

You can submit one application form per year of entry, and usually choose up to two courses.

How to apply

Choosing your course

This course is divided into three progressional levels of study:

  • PG Certificate (PG Cert)
  • PG Diploma (PG Dip)
  • MSc

Each level of study has its own separate entry point; you can apply to any level in the first instance.

Read more about Postgraduate Certificate, Diploma and MSc degrees

Making an application

All applicants to our Master's courses must apply online.

For full details on the online application process, please visit the admissions website.

ATAS certificate

An ATAS certificate is not required for overseas students applying for this course.

Tuition fees and funding

The level of tuition fees you pay is based on your fee status, which we assess based on UK government legislation.

For more information on the funding opportunities that are available, please visit our Fees and Funding website.

Tuition fees and funding

Tuition fees (Home and EU students)

2019 entryFull feeTop-up fee*
MSc £12,000 £4,000
Postgraduate Diploma (PG Dip) £8,000 £4,000
Postgraduate Certificate (PG Cert) £4,000
* If you have already completed one of the above qualifications and are moving on to the next level of study, e.g. you've already completed the PG Cert and want to study the PG Dip, you will only need to pay the top-up fee for the course you’re applying for.

You may apply to enter this programme at any level of study.

If you enter the MSc, without having studied the PG Cert or PG Dip, then you will pay the full fee listed for the MSc.

If you choose to enter at the PG Cert or PG Dip level and return in future academic years to complete a higher award, you will pay the top-up fee instead of the full fee for your chosen course.

If you continue uninterrupted from one award to the next, you will pay the top-up fee above, plus any annual inflationary increases that have subsequently been applied by the College to the 2018 entry fee.

The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value for April 2019 will apply to fees for the academic year 2019–2020.

If you exit the course with an award and return following a break, you will pay the top-up fee advertised in the year of your return.

You could be eligible for a Postgraduate Master’s Loan from the UK government if you apply for the MSc in the first instance.

PG Cert and PG Diploma students are not eligible for the Master's loan since each of these programmes are not worth 90 ECTS credits, which is one of the eligibility criteria for this loan.

Tuition fees (Overseas and Islands students)

2019 entryFull feeTop-up fee*
MSc £34,500 £6,900
Postgraduate Diploma (PG Dip) £27,600 £10,350
Postgraduate Certificate (PG Cert) £17,250
* If you have already completed one of the above qualifications and are moving on to the next level of study, e.g. you've already completed the PG Cert and want to study the PG Dip, you will only need to pay the top-up fee for the course you’re applying for.

You may apply to enter this programme at any level of study.

If you enter the MSc, without having studied the PG Cert or PG Dip, then you will pay the full fee listed for the MSc.

If you choose to enter at the PG Cert or PG Dip level and return in future academic years to complete a higher award, you will pay the top-up fee instead of the full fee for your chosen course.

If you continue uninterrupted from one award to the next, you will pay the top-up fee above, plus any annual inflationary increases that have subsequently been applied by the College to the 2018 entry fee.

The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value for April 2019 will apply to fees for the academic year 2019–2020.

If you exit the course with an award and return following a break, you will pay the top-up fee advertised in the year of your return.

You could be eligible for a Postgraduate Master’s Loan from the UK government if you apply for the MSc in the first instance.

PG Cert and PG Diploma students are not eligible for the Master's loan since each of these programmes are not worth 90 ECTS credits, which is one of the eligibility criteria for this loan.

Postgraduate Master's loan

If you are a Home or EU student who meets certain criteria, you may be able to apply for a Postgraduate Master’s Loan of up to £10,280 from the UK government. The loan is not means-tested, and you can choose whether to put it towards your tuition fees or living costs.

You must apply for the MSc in this course in order to be eligible for a Postgraduate Master's Loan.

Scholarships

We offer a range of scholarships for postgraduate students to support you through your studies. Try our scholarships search tool to see what you might be eligible for.

There are a number of external organisations also offer awards for Imperial students, find out more about non-Imperial scholarships.

Accommodation and living costs

Living costs, including accommodation, are not included in your tuition fees.

You can compare costs across our different accommodation options on our Accommodation website.

A rough guide to what you might expect to spend to live in reasonable comfort in London is available on our Fees and Funding website.

Further information

Microbiome

Got a question?

Enquiries
Eleanor Wilde, Course Administrator
T: +44 (0)20 7594 7767
E: genomic@imperial.ac.uk

Read more about the NHLI and our research on the National Heart and Lung Institute website.

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