An ability to generate immune responses to invading pathogens is vital to our well being and survival yet over-vigorous or inappropriate responses can lead to debilitating or life threatening conditions such as autoimmunity (e.g. diabetes, rheumatoid arthritis) and allergy. Further, as our understanding of disease develops we find that dysregulated inflammatory responses are associated with conditions as diverse as COPD and obesity. An understanding of and an ability to control inappropriate immunity and inflammation lie therefore on the path to successful treatment of these varied diseases. Read more about our research.